The answer largely depends on the college. Catholic colleges offer most, if not all, of the same majors and academic programs that secular colleges do. The main difference between the curriculum at a Catholic college and a non-Catholic college would be required religious courses.
Most Catholic colleges will require students to take a certain number of religious courses in order to graduate. However, these courses are not necessarily limited to classes about the Catholic faith. Catholic college do not require that their students identify as Catholic, and as such they tend to be very welcoming of students of all backgrounds and religions. Many Catholic colleges will allow students to take religious courses that focus on other religions to satisfy their requirement.
Aside from a certain number of required religious courses, which will vary depending on the school, there is not much else that is different between the curriculum at a Catholic university and a non-Catholic University.